Clinical development and trial testing of vesleteplirsen (SRP-5051) for Duchenne muscular dystrophy (DMD) was stopped, with ...

Progressive muscular atrophy (PMA) is a rare disease that affects lower motor neurons, brain cells that provide muscles and glands with the nerves needed to function correctly. People with this ...

Figure 1: Physical map of the BMD region ... The BLAST analysis of the DNA region located upstream of the 5′-terminal exon identified an additional human EST. After correcting sequencing ...

Zinc supplementation showed limited benefits in improving muscle health and hydration in boys with DMD. Nearly 30% of participants had low zinc levels initially, with slight improvement post ...

Miyazaki et al. established three distinct BMD mouse models by deleting different exon regions of the dystrophin gene, observed in human BMD. The authors demonstrated that these models exhibit ...

BMD severity varies from asymptomatic to severe, associated with the genotype of DMD. However, the underlying mechanisms remain unclear. We established BMD mice carrying three representative exon ...

Bionews, Inc., the parent company of this site, has partnered with the following nonprofit advocacy organizations to help further the mission of ensuring that patients and caregivers are able to get ...

The layoffs come three months after the company axed 150 positions in Sanford following a high-profile phase 3 trial failure for its Duchenne muscular dystrophy (DMD) gene therapy candidate.

Teachers aren't the only ones who carefully follow grading systems. Physical therapists use a muscle strength grading system to define how a muscle or group of muscles is performing. PTs commonly use ...

The Eu­ro­pean Med­i­cines Agency’s hu­man med­i­cines com­mit­tee again de­cid­ed not to rec­om­mend the re­new­al of the con­di­tion­al mar­ket­ing au­tho­riza­tion for ...