The San Francisco 49ers face the Los Angeles Rams at 1:25 p.m. PDT on Sunday, Sept. 22 at SoFi Stadium in Inglewood, CA.

On Sunday, the San Francisco 49ers will run into a familiar face on the opposing sideline in Los Angeles. After spending six ...

The San Francisco 49ers (1-1) are visiting the Los Angeles Rams (0-2) on Sunday afternoon in a rivalry game between NFC West ...

Jimmy Garoppolo knows what it feels like as a San Francisco 49er to come to L.A., but now the quarterback is on the other ...

San Francisco 49ers wide receiver Deebo Samuel will be sidelined the next couple of weeks because of a calf strain he endured ...

NFL Week 3 odds, picks, predictions, TV and streaming information for the Sunday football game between the San Francisco ...

Former 49ers players Richard Sherman and Donte Whitner ripped San Francisco's defense for allowing Justin Jefferson's 97-yard ...

In June, Jefferson signed a record-setting deal with Minnesota. The four-year, $140 million contract extension made Jefferson ...

Looking at Sunday’s San Francisco 49ers at LA Rams Week 3 NFL odds, lines and trends. Here’s what you need to know.

San Francisco 49ers left tackle Trent Williams said he wants to play until he's 40 years old, per NFL on CBS. More News: Jets ...

Kyle Shanahan ...

Everything you need to know about the Rams' home game against the NFC West rival San Francisco 49ers, including start time, ...