The Bills hold a 9-8 overall record in the rivalry and are 5-3 in Buffalo. The Jaguars have won the last two meetings (neither in Buffalo) and, counting a 10-3 playoff victory on Jan. 7, 2018, have won four of the last six meetings. The Jags are 2-0 vs. Buffalo in playoff games.

The Buffalo Bills haven't started 3-0 since the 2020 season. And what happened that year? They went to the AFC Championship Game. Perhaps it would be a good omen for the Bills, but a 3-0 start would be tremendous in any regard.